Dose Course 2018_Flipping book
Action limits - Proposed philosophy
Step 3:
Adjust the true dose probability distribution such that the dose limits IDC-C a /2 and IDC+C a /2 coincide with the clinical tolerance limits.
Prescribed dose
Probability distribution for the true dose
Dose (Gy)
TL
is set to a minimum acceptable cure rate
TL
is set to a maximum acceptable complication rate
−D
+D
Clinical tolerance limits
Made with FlippingBook HTML5