Dose Course 2018_Flipping book
Action limits - Proposed philosophy
Step 4:
Define the center of the true dose probability distribution as the lower and upper action limit , respectively.
Prescribed dose
Probability distribution for the true dose
Dose (Gy)
is set to a minimum acceptable cure rate
TL
is set to a maximum acceptable complication rate
TL
−D
D
+
Clinical tolerance limits
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