Biophysical Society 59th Annual Meeting Program Guide

2122-P os B oard B259 STUDYING TROPONIN WITHIN REGULATED ACTIN AT SINGLE MOLECULE RESOLUTION. Christopher Solis-Ocampo , Maria E. Moutsoglou, Gi-Ho Kim, John M. Robinson 2123-P os B oard B260 OBSERVING THE PCA-FORCE RELATIONSHIP WITH A 3-BEAD LASER TRAP ASSAY. Thomas J. Longyear , Sam Walcott, Edward P. Debold 2124-P os B oard B261 ENERGY LANDSCAPES REVEAL THE MYOPATHIC EFFECTS OF TROPOMYOSIN MUTATIONS. Marek Orzechowski, Gerrie P. Farman, Jeffrey R. Moore, Stefan Fischer, William Lehman 2125-P os B oard B262 ESTIMATION OF LOCAL FORCES IN MYOFILAMENTS USING X-RAY DIFFRACTION PATTERNS AND MUSCLE MECHANICS DATA. Momcilo Prodanovic, Djordje Nedic, Thomas C. Irving , Srboljub M. Mijailovich 2126-P os B oard B263 HIERARCHY OF REGULATORY INTERACTIONS IN THE SARCOPLASMIC RETICULUM CALCIUM TRANSPORT COMPLEX. John E. Rubin, Bengt Svensson, Kurt C. Peterson, Seth L. Robia, David D. Thomas, Joseph M. Autry 2127-P os B oard B264 REGULATION OF MYOBLAST PROLIFERATION AND DIFFERENTIATION BY ANOCTAMIN 5 AND 6. Li Xu , Renzhi Han, LiXia Zhao 2128-P os B oard B265 CHARGED VESICLES POTENTLY INDUCE NLRP3 INFLAMMASOME ACTIVATION. Lixia Zhao , Li Xu, Zhenyu Zhong, Yougang Zhai, Liang Qiao, Renzhi Han 2129-P os B oard B266 MITSUGUMIN 56 IS AN MBOAT FAMILY MEMBER AND CONTRIBUTES TO POSTNATAL MUSCLE MATURATION. Myuki Nishi , Bo Van, Shinji Komazaki, Daiju Yamazaki, Ki-Ho Park, Jianjie Ma, Hiroshi Takeshima 2130-P os B oard B267 SUPPRESSED AUTOPHAGY FLUX IN SKELETAL MUSCLE OF AN AMYOTROPHIC LATERAL SCLEROSIS MOUSE MODEL. Yajuan Xiao , Changling Ma, Jianxun Yi, Shaoping Wu, Guo Luo, Xiulong Xu, Pei-Hui Lin, Jun Sun, Jingsong Zhou 2131-P os B oard B268 international travel awardee IMPAIRMENT IN ACETYLCHOLINE RELEASE BY CARDIOMYOCYTES LEADS TO ENHANCED PATHOLOGICAL HYPERTROPHY. Cibele Rocha-Resende , Vania Prado, Marco Prado, Aristobolo Mendes Silva, Silvia Guatimosim 2132-P os B oard B269 MYOPATHIC CHANGES IN MURINE SKELETAL MUSCLE LACKING SYNEMIN. Karla Garcia-Pelagio , Joaquin Muriel, Andrea O´Neill, Patrick Desmond, Richard M. Lovering, Linda Lund, Meredith Bond, Robert Bloch 2133-P os B oard B270 CYTOKINE STIMULATION INDUCES NOX2-DEPENDENT ROS PRODUCTION AND DECREASES MUSCLE FUNCTION. James A. Loehr , Reem Abo-Zahrah, Rituraj Pal, George G. Rodney

Mechanisms of Voltage Sensing and Gating (Boards B271-B291) 2134-P os B oard B271 AN EXPERIMENTALLY-VALIDATED MODEL STRUCTURE OF THE HV1 PROTON CHANNEL VOLTAGE SENSOR IN ITS RESTING STATE. Younes Mokrab, Ashley Bennett, Mark S. P. Sansom, I. Scott Ramsey 2135-P os B oard B272 UNVEILING POTENTIAL BINDING SITES IN THE HV1 FOUR HELIX BUNDLE. Eleonora Gianti , Lucie Delemotte, Vincenzo Carnevale, Francesco Tombola, Douglas Tobias, Michael L. Klein 2136-P os B oard B273 ALLOSTERIC COUPLING BETWEEN OPEN SUBUNITS IN THE HV1 PROTON CHANNEL PROBED BY GUANIDINO- THIAZOLES. Liang Hong , Vikrant Singh, Heike Wulff, Francesco Tombola 2137-P os B oard B274 CHARACTERIZATION AND SUBCELLULAR LOCALIZATION OF HV1 IN LINGULODINIUM POLYEDRUM CONFIRMS ITS ROLE IN BIOLUMINESCENCE. Juan D. Rodriguez , Saddef Haq, Kristine F. Nowak, Deri Morgan, Vladimir V. Cherny, Steven Bernstein, Maredith S. Sapp, John R. Curcuru, Coretha Antchouey, Scott J. Nowak, Allen Place, Thomas E. DeCoursey, Susan M E Smith 2138-P os B oard B275 ENGINEERED VOLTAGE SENSING PHOSPHATASES: WHAT DO THEY TELL US ABOUT THE GATING MECHANISM? Angeliki Mavrantoni, Kirstin Hobiger, Michael G. Leitner, Dominik Oliver, Christian R. Halaszovich 2139-P os B oard B276 education travel awardee THE ROLE OF THE C2 DOMAIN OF VOLTAGE SENSING PHOSPHATASE (VSP). Kevin D. Zolman , Paul M. Castle, Susy C. Kohout 2140-P os B oard B277 INVESTIGATING THE FUNCTION OF A NOVEL VOLTAGE- SENSING PROTEIN. Erika Babikow , Ferenc Papp, Suvendu Lomash, Jamie Smith, Kenton Swartz 2141-P os B oard B278 education travel awardee PUTATIVE VOLTAGE SENSITIVE ENZYMES IN PROKARYOTES. Joshua P. Clark , Susan M. E. Smith 2142-P os B oard B279 SEQUENCE SIGNATURE OF VOLTAGE SENSING DETECTED VIA DIMENSIONALITY REDUCTION TECHNIQUES. Daniele Granata , Matteo Marsili, Michael L. Klein, Vincenzo Carnevale 2143-P os B oard B280 LIPID-DEPENDENT CONFORMATIONAL TRANSITIONS IN KVAP ARE DRIVEN BY VOLTAGE SENSING DOMAIN. Qufei Li , Julia Skalska, Sherry Wanderling, Eduardo Perozo 2144-P os B oard B281 MOLECULAR DETERMINANTS OF TEMPERATURE DEPENDENT GATING OF ION CHANNELS. Sandipan Chowdhury , Brian W. Jarecki, Baron Chanda 2145-P os B oard B282 THE GATING CHARGE OF KV1.2 IS LESS THAN EXPECTED FROM ITS SIMILARITY TO SHAKER. Itzel G. Ishida , Gisela E. Rangel-Yescas, Leon D. Islas

130

Biophysical Society 59 th Annual Meeting, Baltimore, Maryland