Biophysical Society 59th Annual Meeting Program Guide

319-P os B oard B99 STUDYING α -SYNUCLEIN MISFOLDING THROUGH FÖRSTER RESONANCE ENERGY TRANSFER. Conor M. Haney , Rebecca F. Wissner, E. James Petersson 320-P os B oard B100 INVESTIGATING THE TRIMETHYLAMINE N-OXIDE (TMAO) INDUCED STRUCTURE OF α -SYNUCLEIN. John J. Ferrie , Rebecca F. Wissner, E James Petersson 321-P os B oard B101 FROM MONOMERS, DIMERS TO OLIGOMERS: HOW METAL IONS REGULATE AMYLOID BETA PORTEINS IN AMYLOID FORMATION? Liang Xu , Buyong Ma 322-P os B oard B102 TRANSIENT BINDING OF ZN(II )REDIRECTS AMYLOID BETA PEPTIDE FROM FIBRIL FORMATION. Astrid Graslund , Axel Abelein, Jens Danielsson 323-P os B oard B103 SITE-SPECIFIC DYNAMICS OF A β 1-23 AMYLOID FORMATION AND FIBRILLAR CONFIGURATION USING AN UNNATURAL AMINO ACID. Deguo Du , Haiyang Liu, Richard Lantz, Patrick Cosme, Andrew C. Terentis, Ewa P. Wojcikiewicz, Rolando Oyola 324-P os B oard B104 minority affairs travel awardee SURFACE INTERACTIONS RESTRICTS AMYLOID‑ β PEPTIDES MOVEMENTS RESULTING IN THEIR RAPID SELF-ASSEMBLY INTO β SHEETS; A MOLECULAR DYNAMICS STUDY. Natnael B. Doilicho , Karl F. Freed, Esmael J. Haddadian 325-P os B oard B105 BINDING OF A β MONOMER TO DMPC BILAYER USING ISOBARIC-ISOTHERMAL REPLICA EXCHANGE MOLECULAR DYNAMICS. Christopher Lockhart , Dmitri K. Klimov 326-Pos Board B106 AMYLOID- β OLIGOMERS: NOW FOR THE STRUCTURE IN THE MEMBRANE. Debanjan Bhowmik, Sudipta Maiti, Kaustubh Mote, Bappaditya Chandra, Perunthiruthy Madhu 327-P os B oard B107 SMALLER LIPOSOMES ACCELERATE THE FIBRILLATION OF AMYLOID β (1-40). Mayu S. Terakawa 328-P os B oard B108 AMYLOID FIBRIL NUCLEATION IN REVERSE MICELLES. Gozde Eskici , Paul Axelsen 329-P os B oard B109 MICROTUBULE NETWORKS MODULATE CELLULAR SUSCEPTIBILITY TO A β -MEDIATED TOXICITY. Nicole Shamitko- Klingensmith, Jonathan W. Boyd, Justin Legleiter 330-P os B oard B110 RECONFIGURATION OF THE ALZHEIMER’S PEPTIDE KINETICALLY CONTROLS AGGREGATION IN ALZHEIMER’S DISEASE. Srabasti Acharya, Lisa J. Lapidus 331-P os B oard B111 education travel awardee THE ABILITY OF POLYPHENOLS TO REDUCE A β -INDUCED APOPTOSIS ASSOCIATED WITH ALZHEIMER’S DISEASE. Kayla M. Pate , McCall Rogers, Melissa Moss 332-P os B oard B112 SELF-PROPAGATIVE REPLICATION OF AMYLOID- β OLIGOMERS IN ALZHEIMER DISEASE. Dexter N. Dean , Amit Kumar, Kayla M. Pate, Melissa A. Moss, Vijayaraghavan Rangachari

333-P os B oard B113 ALZHEIMER’S PROTECTIVE A2T MUTATION CHANGES THE CONFORMATIONAL LANDSCAPE OF THE A β 1-42 MONOMER DIFFERENTLY THAN DOES THE A2V MUTATION. Payel Das 334-P os B oard B114 THE EFFECT OF PEPTOIDS ON A β AGGREGATION AND NF- κ B ACTIVATION IN ALZHEIMER’S DISEASE. Kelly Moore, Lauren M. Wolf , J. Phillip Turner, Melissa A. Moss, Shannon Servoss 335-P os B oard B115 EFFECTS OF CARBON NANOPARTICLES ON THE AGGREGATION OF ALZHEIMERS BETA-AMYLOID PEPTIDE. Yunxiang Sun, Luogang Xie, Dongdong Lin, Xinju Yang, Guanghong Wei DNA Replication, Recombination, and Repair (Boards B116-B136) 336-P os B oard B116 SINGLE MOLECULE STUDIES OF RPA’S SEQUENTIAL BINDING TO SSDNA REVEALS A HIGHLY STIFF AND STABLE STATE INDUCED BY THE BINDING OF ZINC. Jin Chen , Shimin Le, Walter J. Chazin, Jie Yan 337-P os B oard B117 STUDIES OF THE FTSK DNA TRANSLOCASE USING TWO- COLOR TETHERED FLUOROPHORE MOTION. Peter F J May , Pawel Zawadzki, Lidia K. Arciszewska, David Sherratt, Achillefs N. B oard B118 UNRAVELING THE INTERPLAY BETWEEN SINGLE-STRANDED DNA-BINDING PROTEIN, DNA POLYMERASE AND SINGLE- STRANDED DNA. Jordi Cabanas Danes , Tjalle P. Hoekstra, Iddo Heller, Erwin J.G. Peterman, Gijs J.L. Wuite 339-P os B oard B119 MECHANISTIC INSIGHTS OF HEXAMERIC HELICASE FUNCTION PROVIDED BY SINGLE-MOLECULE FRET. Sean M. Carney , Sanford Leuba, Michael Trakselis 340-P os B oard B120 EFFECTS OF DNA STRUCTURAL AND TOPOLOGICAL CONSTRAINTS ON HMGA2 BINDING. Xiaodan Zhao , Peter Dröge, Jie Yan 341-P os B oard B121 SINGLE-MOLECULE ANALYSIS OF TRANSCRIPTION-COUPLED REPAIR. Jun Fan , Nigel Savery, Nicolas Joly, Terence Strick 342-P os B oard B122 INVESTIGATION OF THE TUS-TER BLOCKING EFFICACY DURING THE CHROMOSOME REPLICATION OF LIVE ESCHERICHIA COLI CELLS. Sriram Tiruvadi Krishnan , M. Charl Moolman, Roy de Leeuw, Jacob W.J. Kerssemakers, Nynke H. Dekker 343-P os B oard B123 EXTREMOPHILE DNA PHOTOLYASES: DNA REPAIR UNDER EXTREME CONDITIONS. Sudipto Munshi , Brittany N. Stroud, Yvonne M. Gindt, Robert J. Stanley 344-P os B oard B124 STRUCTURE AND NANO-MECHANICS OF DNA DURING THE INITIAL STAGES OF METHYL-DIRECTED MISMATCH REPAIR. Eric A. Josephs , Piotr E. Marszalek Kapanidis 338-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland