Basic Clinical Radiobiology 2017

T-cell priming

Herrera FG et al CA Cancer J Clin 2017

• Agonistic antibodies directed against costimulatory molecules on T-cells and/or blocking antibodies against coinhibitory molecules to increase T-cell function • E.g. CTLA-4 blockade (ipilimumab)

Ribas, NEJM 2015