Gynae BT 2017

PARCER, primary endpoint late bowel morbidity

Chopra ASTRO, 2015

Median Follow Up = 20 months

•

• 14% absolute difference in late Grade ≥ 3toxicity

• Statistically insignificant at interim analysis

IG-IMRT

3DCRT

p value

Late Grade ≥ II toxicity

11.4%

25%

0.13

(Primary Endpoint)

Late Grade ≥ III toxicity

3.2%

17.8%

0.02

(Exploratory Endpoint)