AOAC Annual Meeting_AIMS

Norovirus

• Leading cause of gastroenteritis worldwide • Over 5 million cases in US annually • Norovirus non-enveloped viruses • + ss RNA genome 7.5 kb • 5’ end covalently linked to VPg and 3’ poly A tail • 3 ORFs and murine norovirus has 4 ORFs • Murine norovirus has complex genome