Basic Training 4th Annual ICP Conference

Iodine in biologicals

1 – Planning Iodine (blood, urine, etc.) - As iodide ( I - ) - Complexed with proteins - 5 – 2000 µg/L (ppb) Detection limits/uncertainty Chemical composition

90-95% water protein, fat, carbohydrates (C, N) pH = 6 - 7

IDLs: OES = 20 – 1000 ppb MS = 2 – 50 ppb

Iodine in biologicals

2 – Sample Preparation Possible approaches

Advantages

Disadvantages

1. Acid digestion 2. Base digestion 3. Ashing/fusion 4. Dilute-and-shoot

minimal equipment, few reagents

chemistry

minimal equipment, few reagents

few, if any

minimal equipment

volatility, flux matrix

simple

none

Possible concerns ! Iodide

Iodine