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Replanning H&N IMRT patients

Causes of anatomy variations:

Tumor shrinkage

Weight loss (mucositis, reduced caloric intake)

Radiation induced anatomical changes (parotid glands)

Significant variations for dose to OAR (generally increased)

Variations of target coverage

Adaptive RT

Castadot, P., Lee, J. a., Geets, X. & Grégoire, V. Adaptive Radiotherapy of

Head and Neck Cancer. Semin. Radiat. Oncol. 20, 84–93 (2010).