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Radiation-induced secondary cancer
after breast cancer radiotherapy
•
Most second cancers after radiotherapy are attributed to other factors,
e.g. lifestyle and genetics
Berrington de Gonzales Lancet Oncol 2011
•
Contralateral breast cancer:
In patients < 40 years: if mean dose > 1 Gy (dose-dependent)
Stovall IJROBP 2008
•
Induction of non-breast cancer, e.g. lung, esophagus
Low risk compared to benefit of radiotherapy
Grantzau RO 2015, Taylor JCO 2017