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Breast fibrosis – non-RT risk factors

Adjuvant systemic therapy

Post-operative breast oedema or hematoma / seroma in tumor bed

Fibrosis, fat necrosis, hyperpigmentation

Bartelink Lancet Oncol 2015, Collette Eur J Cancer 2008, Mukesh Radiother Oncol 2012. BrouwersRO 2018