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Hard data: microscopic extensions in

lung cancer

30% patients with low

grade tumors (now

treated with SBRT with

few mm margins), have

spread at 15 mm distance

Having dose there may be essential!

100%

50%

25%

Slide courtesy of Gilhuijs and Stroom, NKI

N=32

0

10

20

30

40

50

60

70

80

90

100

0 5 10 15 20 25 30 35 40 45

distance from GTV [mm]

% cases with extensions

Deformation

corrected