SBRT: wide use,
high heterogeneity
M. Guckenberger et al. JTO 2013:
n=582, 13 institutions, SBRT 1998 - 2011
7 · 1. Oktober 2018
Number of
patients
Percentage Median Minimum Maximum
Time-
trend
Inter-
institutional
variability
Dose calculation algorithm
p<0.001 p<0.001
Type A
265
45.5
Type B
249
42.8
unknown
68
11.7
Number of SBRT fractions
582
3
1
20
0.02
p<0.001
Single fraction dose PTV
encomassing (Gy)
582
12.5
2.9
33.0
NS p<0.001
Total dose PTV encompassing (Gy)
582
37.5
12.0
64.0 p<0.001 p<0.001
Dose inhomogeneity (PTV
encompasing dose / Maximum PTV
dose) (%)
582
65
60
100
NS p<0.001
Total BED dose PTV encompassing
(Gy)
582
84.4
38.3
180.0 p<0.001 p<0.001