821 / 1161
Summary
• in high-precision radiotherapy enabling hypofractionation,
effective tumor doses often exceed normal tissue tolerances
• a relevant problem are critical serial normal tissues near high-
dose targets, as exceeding tolerance doses here may lead to
life-threatening consequences for the patient
• advanced treatment strategies therefore need the discussion of
compromises
• beyond adapting dose and fractionation, local strategies may
help to ensure high TCP