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Can we derive an internal target volume from 3D PET?

12 NSCLC scheduled for SBRT; 4D PET/CTs, 4 observers:

1. ITV in 4D CT „gold standard“

2. „GTVs“ in 3D PET

3. ITVs from 4D PET

- manual

- Homburg algorithm

- Rover algorithm

- 40% SUVmax

- 15% SUVmax

26

0

5

10

15

20

25

30

manual mean HOM Rover

40% 15%

ITV-4D CT

3D-GTV-PET

ITV- 4D PET

ml