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Materials and Methods

Six prostate cases were replanned using probabilistic

objective functions aiming for identical target coverage

All plans were evaluated using independent geometrical

uncertainties simulation software (UNCERT)

10.000 patients x 39 fractions simulated per plan

Uncertainty values (1SD): setup errors + organ motion

Translation errors

(mm)

LR AP SI

Preparation (systematic)

S

k

2.6 3.5 2.4

Execution (random)

s

k

2.0 3.0 2.4

21

prostate

and

rectum