Course book Advanced Treatment Planning 2018

Hypoxia Dose Painting Trail in Tübingen,

Germany

• Definition of hypoxic volume

(HV) according to [

F]-

FMISO PET/CT

• Dose escalation of 10%

(77Gy) in the HV inside the

PTV70 in the experimental

treatment arm

• Isotoxic approach!

• So far n=26 patients included.

PTV70

PTV60

PTV54

IMRT plan for patient #3 in the HDP trial.

7| D. Thorwarth | 06.04.2014 ESTRO 33