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Column1 Column2

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Column5

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Disease Site Total

Randomized / P III

P I/II P0 / Pilot / Reg

Completed

C-Ion

Breast (PB, Lymphnodes, Hodgkins,…)

14

1

9

4

2

CNS (Skull Base, Spine, Brain, …)

25

2

17

6

1

5

Eye (Melanoma, ReQnoblastoma, Mdeg,

…)

9

0

6

3

2

GI (upper GI, Esophageal, Rectum, …)

6

1

2

3

3

1

H&N Nasal Cavity, Nasopharynx,

Oropharynx,…)

20

2

7

11

5

6

Lung (NSCLC)

27

1

16

10

7

Lymphoma (Hodgkin Lymphoma, …)

4

0

1

3

1

GI (Liver)

16

2

10

4

3

GI (Pancreas)

12

0

12

0

1

1

Pediatrics (CNS, RMS, Meduloblastoma,

H&N, Brain, ...)

23

0

11

12

4

GU (Prostate)

24

8

9

7

4

1

GU (Bladder, Gyn)

2

0

1

1

0

Sarcoma (Chordoma, Chondrosarkoma,

Spine, …)

17

1

13

3

4

2

Total

199

18 114

67

37 16

* Informa4on compiled by PTCOG from par4cle therapy centers and from ClinicalTrials.gov – January 2016

Clinical Trials (acQve or completed) in ParQcle Therapy:

The PTCOG List

Note: Data form centers in Japan largely not reported to PTCOG