Particle Therapy 2017

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Influence of OAR Dose Constraints on Target Coverage

Example: Chordoma of upper Clivus with small residual disease

Proton Therapy: 1.8 Gy(RBE) per fracCon CTV: 54 Gy(RBE); GTV 73.8 Gy(RBE)

OAR Constraint:

60

Gy(RBE) Op+c Nerves

and Chiasm

64

Gy(RBE) Brainstem

Surface

OAR Constraint:

54

Gy(RBE) Op+c Nerves

and Chiasm

58

Gy(RBE) Brainstem

Surface

Red

: GTV’s

CTV not

shown