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CIRT

intensifica.on

Dose

escala.on

N

frac.on

unchanged

5% dose increments

Hypofrac.ona.on

Dose unchanged

N

frac.on

16 -> 12 -> 8 -> 4 -> 2 -> 1

Parameters that favor of dose escalation?

Parameters that favor of hypofractionation?

Low LET

High

LET