Binder1

both, the chromatographic conditions of separation and quantitative analysis, as well as

sample preparation approach for efficient isolation of the analytes (eg., pesticides, 5-

nitroimidazoles (NDZs), sulfonated azo dyes, drugs, bisphenol A and its metabolites)

form different food samples and subsequent extract clean-up. Sample preparation

procedures for the analysis of various commodities, including sunflower seeds, edible

oils, milk, soya milk, wines, different beverages, candies and caviar/fish roe, were

developed by the optimization of the conditions of analytes isolation from complex

matrices and extracts clean-up. For that purpose, different extraction and clean-up

techniques were used, mainly QuEChERS (quick, easy, cheap, effective, rugged and

safe), ultrasound assisted extraction (UAE), solid-phase extraction (SPE), dispersive-SPE

(d-SPE) and matrix solid-phase dispersion (MSPD).

Additional of research (2017, in cooperation) were:

- application of mobile phases containing ionic liquid for the separation of a mixtures of

selected isoquinoline alkaloids by 2D-TLC and identification of analytes in

Coptidis

Rhizoma

(Huang Lian) extract and

Thalictrum foetidum

root extract by TLC and HPLC–

DAD;

- identification and quantitative analysis of new cancer prodrug in the serum samples: the

determination of ethyl [4-oxo-8-(3-chlorophenyl)-4,6,7,8-tetrahydroimidazo[2,1-

c][1,2,4]triazin-3-yl]acetate (ETTA), a new anticancer prodrug, using adsorptive

stripping voltammetry (AdSV) - was published for the first time.