1009 / 1119
LOCAL CONTROL - CLINICAL DATA/AIMS
DOSE at POINT A vs. as D90 IN IMAGE GUIDED ADAPTIVE BT
EARLY DISEASE
DOSE
Pt A / D90 HR
BEST
STANDARDS*
AIM
75 Gy / 85-95+
Gy
90-95%
~100%
ADVANCED
DISEASE
IIB<5cm
80 Gy / 85-90
Gy
70-85%
95-100%
IIB/IIIB>5cm
85 Gy / 90+ Gy
50-65%
85-90%
Expected Improvement through Image Guided Adaptative BT
local control by 5-40%; overall survival by 2-20% (?)
* Including a gain through chemoradiation of 5-10%