138 / 1119
N= 115
BT
EBRT
stage IB2 - IVA
Volume change during treatment
V
2
V
3
V
4
V
1
PV = 100 %
PV = 87 %
PV = 40 %
PV = 31 %
0
20
40
60
80
100
1
2
3
4
Proportional Volume [%}
•Rapid response: 2.2% / Gy
•Steep slope
•Low AUC (24 %)
•Slow response: 0.8% / Gy
•Low slope
•High AUC (50 %)
Alive & well
at 7 y
LR at 1 y
Death at 2 y
Regression to
P
roportional
V
olume:
PV = V
x
/ V
1
[%]
S
ize of the tumor at Brachytherapy
Mayr NA, et al. Int J Radiat Oncol Biol Phys 2010