Hyperthermia & Brachytherapy
Datta NR, et al. Cancer Treatment Reviews 2015;41:742-753.
Mallory M, et al. Critical Rev in Oncol / Hematol 2016;97:56-64.
Warrel G, et al. Med Phys. 2015;42(6):3709.
Chen X, et al. Int J Hyperthermia. 2010;(1):39-55.
Lutgens L, et al. Cochrane Database Syst Rev CD006377
Franckena M, et al. IJROBP 2008;70:1176-1182.
Franckena M, et al. IJROBP 2009;73:242-50.
Franckena M, et al. Eur J Cancer 2009;45:1969-1978.
From: Datta NR, et al. Cancer Treatment Reviews 2015
RT+HT
RT
Pelvic tumor control
Years
RT+HT
RT
Overall survival
Years
“Dutch hyperthermia trial, 12 y FU”
Toxicity: comparable
Franckena M, et al. IJROBP 2008;70:1176-1182.
Historical
Paris
Stockholm
Manchester
Fletcher
Limitations of
IC Applicators
Modern
Stockholm
Manchester
& Fletcher
Mould
Complete
remission
Local
recurrence
Overall
Survival
Lutgens L, et al. Cochrane Database Syst Rev CD006377
Emerging
Technologies