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Hyperthermia & Brachytherapy

Datta NR, et al. Cancer Treatment Reviews 2015;41:742-753.

Mallory M, et al. Critical Rev in Oncol / Hematol 2016;97:56-64.

Warrel G, et al. Med Phys. 2015;42(6):3709.

Chen X, et al. Int J Hyperthermia. 2010;(1):39-55.

Lutgens L, et al. Cochrane Database Syst Rev CD006377

Franckena M, et al. IJROBP 2008;70:1176-1182.

Franckena M, et al. IJROBP 2009;73:242-50.

Franckena M, et al. Eur J Cancer 2009;45:1969-1978.

From: Datta NR, et al. Cancer Treatment Reviews 2015

RT+HT

RT

Pelvic tumor control

Years

RT+HT

RT

Overall survival

Years

“Dutch hyperthermia trial, 12 y FU”

Toxicity: comparable

Franckena M, et al. IJROBP 2008;70:1176-1182.

Historical

Paris

Stockholm

Manchester

Fletcher

Limitations of

IC Applicators

Modern

Stockholm

Manchester

& Fletcher

Mould

Complete

remission

Local

recurrence

Overall

Survival

Lutgens L, et al. Cochrane Database Syst Rev CD006377

Emerging

Technologies