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GTV = Gross Tumor Volume

Macroscopic tumor, visible clinically and with imaging

CTV = Clinical Target Volume

Tissue volume that contains a GTV and/or subclinical

microscopic malignant disease, which has to be

eliminated

ITV = Internal target volume

Volume that accounts for internal inter- and intra-

fraction motion and deformation of the CTV

CTV

ITV

GTV

Definitions

(upcoming definitions in the frame of adaptive thinking)

ICRU reports