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Page Background

Uterus & cervix: embryological one unit

interconnected lymphatics

no separating fascial plane

Challenging to determine myometrial invasion

Trachelectomy, early stage disease

a

:

Local recurrence < 5 %, Mortality < 3%

Uterine recurrences

b,c,d

2 %

Trachelectomy, tumor > 2 cm or lymphovascular invasion

a,e

:

Local recurrence up to 10 %

Allowing for some dose reduction to the fundus in cases

without uterine infiltration will be investigated in future

Lim K, et al. IJROBP 2010

a

Plante M. Gynecol Oncol 2008

b

Bali A, et al. Gynecol Oncol 2008

c

Diaz JP, et al. Gynecol Oncol 2008

d

Hertel H, et al. Gynecol Oncol 2006

e

Nishio H, et al. Gynecol Oncol 2009

Why the entire uterus?

Rationale