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From: Lim K, et al. Image guidance...In: Viswanathan et al., eds. Gyn Radiat Oncol. Springer 2011

Chan P, et al. IJROBP 2008, Taylor A, et al. Radiother Oncol 2008, Georg D, et al. Strahlenther

Onkol 2006, Roeske JC, et al. Radiother Oncol 2003, van de Bunt L, et al. Radiother Oncol 2008,

bowel

• Several studies deal with tumor motion

• MRI studies provide best insight

• Large inter- fraction motion is found in majority of studies

= CTV + margin for internal motion & deformation

ITV-T – Internal Target Volume