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Dose volume relationship for

Gross nodes

• No clear consensus

• Escalation typically recommended upto 55-60Gy.

• SIB IMRT – 55Gy/25# with option of sequential

boost -10Gy/5#

• FDG avid nodal disease -62Gy/31# SIB (primary

tumor treated at 1.8Gy/#

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Grigsby PW, et al Int J Radiat Oncol Biol Phys 2001, 49(3):733–738.

-Beadle BM, et al Int J Radiat Oncol Biol Phys 2010, 76(5):1396–1403.