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BT-GYN Teaching Course

D. Berger

Survival curve according to the LQ-model

Linear-Quadratic Model

1,E-04

1,E-03

1,E-02

1,E-01

1,E+00

0

5

10

15

20

dose (Gy)

proportion of surviving cells

²)

(

DD

e S

β

α

+ −

=

-> Lethal damage

-> Sublethal damage

remember survival curve by Puck and Marcus

α

D

β

α/β

This can be used to fit a continuously bending curve to cell survival data