Molecular Imaging 2017

1116 / 1241

FDG PET/CT guided Dose Painting by
Contours in HNC
Madani et al, IJROBP 2007
• n=41 patients
• Phase I study
• 2 different dose levels:
– Dose level I: 25 Gy (n=23)
– Dose level II: 30 Gy (n=18)
– 22 fx à 2.16 Gy
• 2 cases of dose-limiting toxicity at
dose level I
• 1 treatment related death (dose
level II)
• Manual GTVPET delineation
in 10 fx