Molecular Imaging 2017

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Analysis of tumor heterogeneity
ADCmin ADC max
ADC SUV
SUV
max
SUV
min
Positive Spearman
correlation,
Low mutual
information
FDG and ADC may identify different
volumes for dose painting. This may have
severe consequences on the resulting dose
distribution!
• N=18 HNC patients
• Examined with FDG PET and DW-MRI
• Voxel-based correlation of ADC values and FD uptake
• Comparison of ADC- and FDG-based volumes for
potential RT dose escalation
Houweling A et al. Radiother Oncol 2013;106(2):250-4.