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Summary/Conclusion
Functional Imaging
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Can visualize a variety of different biological /functional
tumor properties
Key Issues for Dose Painting
•
How to translate functional imaging information into
dose prescriptions?
?
Robustness
?
Automation
?
Which imaging parameter to use?
?
Resolution?
?
Prescription Function
Multi-parametric imaging for Dose Painting
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Investigate tumor heterogeneity, in combined imaging studies
•
Investigate local response to establish image-based dose-
effect relations
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Dose-effect relations based on mp-imaging properties