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Spectro glio trial

robust and reproducible technique for MR spectroscopy coregistration with

planning CT.

Dosimetric comparaison on 16 patients :

IMRT SIB technique 72 Gy compared with 3D conformal RT 60 Gy :

better target coverage,

better index conformity

better conformation number

equivalent or better OARs sparing

.

Ken et al, Radiation Oncology 2013

0,00%

10,00%

20,00%

30,00%

40,00%

50,00%

60,00%

V18 (18 Gy)

V36 (36 Gy)

V50 (50Gy)

Dose-volumes

relative to

normal brain

(%volume)

60-Gy 3D-CRT

60-Gy IMRT

72-Gy SIB-IMRT

MR spectroscopic imaging for dose-painting

25