1216 / 1241
220 patients – 9 institutions
60 Gy + TMZ + 72 Gy/2,4 Gy
IMRT SIB guided by MR spectroscopy
Global survival
MRI + spectro /2months
Randomization
MRI + spectro
60 Gy + TMZ
SPECTRO GLIO
Newly Diagnosed Glioblastoma
Prospective multicentric phase III trial
Promoted by IUC Toulouse coordinator A Laprie– financed by French national cancer institute
MR spectroscopic imaging for dose-painting
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