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The PROMIS study
mP-MRI prior to biopsy
Recruitment: 740 males (target 715)
TPM (reference standard) & TRUS biopsy (current standard)
To assess the ability of MP-MRI to identify men who can safely
avoid unnecessary biopsy
To assess the ability of the MP-MRI based pathway to improve
the rate of detection of clinically significant cancer as
compared to TRUS biopsy
To estimate the cost-effectiveness of an MP-MRI based
diagnostic pathway
El-Shater Bosaily et al. Contemp Clin Trials. 2015 May;42:26-40