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FDG-PET/CT in response assessment
Pre-treatment FDG-PET/CT shows the anal
tumor on axial slices and shows a left
inguinal node (white arrow) (A).
Corresponding images, obtained on post-
treatment FDG-PET/CT show persistent
increased FDG uptake in anal canal
(considered as non complete response), but
complete regression of inguinal node uptake.
Persistent disease was proven by biopsyed 4
months after chemoradiotherapy (B),
Pre-treatment FDG-PET/CT shows the anal
tumor on axial slices (A). Corresponding
images, obtained on post-treatment FDG-
PET/CT performed 3 months after
chemoradiotherapy (B), show low FDG
uptake (complete metabolic response). At
the end of follow-up the patient was alive and
without evidence of recurrence.
Example of Complete Metabolic Response
Example of partial metabolic response
High sensitivity (92%) and high negative predictive value (96.4%)
Houard et al
.
JNM 2017