343 / 1241
SSP
RC versus non RC à S11
0 1 2 3 4 5 6 7 8 9 10
0
20
40
60
80
100
80 %
72 %
PR
CR
Years
SSP (%)
HR = 0,71 ; IC
95
: 0,53-0,95 (p = 0,02)
Years
0 1 2 3 4 5 6 7 8 9 10
HR = 0,21 ; IC
95
: 0,15-0,29 (p < 0,001)
20
40
60
80
100
0
PR
CR
83 %
45 %
SSP (%)
SSP
RC versus non RC à S26
ASCO
®
2012 - D
’
après Glynne-Jones R et al., abstr. 4004 actualisé
Optimal time for response assessment ?
Response assessment at W11 seemed too early : 60 % of patients considered with partial
response at S11 were in complete remission at W26
Except in the case of progression, it is necessary to wait until 4-6 months after the
end of radiochemotherapy, before discussing a salvage surgery in case of residual
tumor