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Wanet M et al. Radiother

Oncol 2011;98:117-25.

N=10 NSCLC patients

GTV delineation on CT

±

PET

Comparison with surgical

specimen

PET yields more robust

delineation in poorly

defined tumors

Gradient based seg. outper-

formed threshold method in

terms of accuracy and

robustness

Gradient-based PET segmentation improves

target volume definition in NSCLC