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Amino Acid Imaging (MET/FET)
Binding reflects amino acid
(i.e. methionine) transport
Principle:
•
High tumor/background ratio
(in brain)
•Independent from BBB disturbance
• Relatively specific for malignancies
• [
123
I]-IMT SPECT widely available
• Limited usefulness outside brain
• Fusion with MRI/CT mandatory
• Very limited availability
([
11
C]methionine)
Disadvantages:
Advantages: