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11C-MET-PET versus 18F-FET-PET

Despite the considerable number of encouraging results,

the application of MET-PET in diagnosis of brain tumors

has been mainly limited to a small number of centers. The

short physical half-life of carbon-11 (20 min) necessitates

an on-site cyclotron for MET-PET examination, making the

utilization of this tracer for the PET investigation difficult.

In contrast to MET the physical half time for 18F of 110

minutes allows performing the FET-PET studies in centers

without an on-site cyclotron.