Index
969
drug–drug interactions, 543
pharmacokinetics, 540, 543
routes of administration, 544
therapeutic actions and indications,
540
mineralocorticoids, 536, 542–543,
547–548
adverse effects, 547
care considerations, 548
contraindications and cautions, 547
drug–drug interactions, 547
duration of effect, 539
pharmacokinetics, 547
therapeutic actions and indications,
547
Adventitia layer, 890
Adverse effects, 2, 3, 31–33
managing, 46
Adverse reactions, 86–87
gastrointestinal toxicity, 87
hypersensitivity reactions, 87
kidney damage, 86
neurotoxicity, 87
superinfections, 81, 87
Aerobic bacteria, 90, 91
Affect, 316, 317
Afferent fibres, 292, 293
African sleeping sickness, 163, 172
Age, 45
drug effects, 25, 26
Agomelatine, 330, 331
Agonists, 15, 17
AIDS.
See
HIV and AIDS
Albendazole, 183, 185, 186
Aldesleukin, 258, 261, 262
Aldosterone, 794, 797
Alemtuzumab, 266
Alendronate, 552, 566, 567–568
Alfalfa, 962
Alfentanil, 401, 402
Alfuzosin, 475–476, 828, 829
Alkalosis, 803, 810
Alkylating agents, 190, 195–199
adverse effects, 197–198
care considerations, 198–199
contraindications and cautions, 195,
197
drug–drug interactions, 198
pharmacokinetics, 195
protective drugs, 198
therapeutic actions and indications, 195
Allergenic extracts, 274
Allergies, 33
delayed reaction, 33, 34
history, 44
Allspice, 962
Aloe leaves, 962
Alogliptin, 586, 588
Alopecia 184, 198
Alpha- and beta-adrenergic agonists, 455,
456–460
adverse effects, 459
care considerations, 459–460
contraindications and cautions, 459
drug–drug interactions, 459
pharmacokinetics, 458
subdivision of receptors, 456–457
therapeutic actions and indications,
457–458
Alpha-glucosidase inhibitors, 573, 586,
588
Alpha-receptors, 444, 448
subdivision, 456–457
Alpha-specific adrenergic agonists,
462–465, 677–678
adverse effects, 463, 677
care considerations, 464–465, 677–678
contraindications and cautions, 463,
677
drug–drug interactions, 463, 677
pharmacokinetics, 463, 677
therapeutic actions and indications,
462–463, 677
Alpha
1
-selective blocking agents, 469,
475–477
adverse effects, 476
care considerations, 476–477
contraindications and cautions, 476
drug–drug interactions, 476
pharmacokinetics, 476
therapeutic actions and indications, 476
Alprazolam, 200, 305, 306
Alprostadil, 635, 636
Alteplase, 757, 764
Alternative and complementary therapies,
60, 962–967
adrenergic blocking agents, 471
antidepressants and, 328
antidiabetic, 582
antifungal agents and, 154
antiseizure agents, 358
antiviral drugs and, 128
benign prostatic hyperplasia, 828
cancer and, 205
female reproductive system, 613
herbal medicine, 63–64
male reproductive system, 632
psychotherapeutic agents, 346
Aluminium
therapeutic effect, 5
Aluminium acetate, 950
Aluminium hydroxide, 900, 904–905
Aluminium salts, 900, 904–905
Alveoli, 834, 835
Alzheimer’s disease, 487, 493
agents for, 487, 492–496
cultural considerations, 493
new drug, development of, 494
Amantadine, 130, 374–376
Amethocaine, 425, 426
Amides, 425
Amifostine, 197, 198
Amikacin, 95
Amiloride, 675, 806, 813
Aminocaproic acid, 769, 770
Aminoglycosides, 90, 95–97
adverse effects, 96
care considerations, 96–97
contraindications and cautions, 95–96
drug–drug interactions, 96
pharmacokinetics, 95
therapeutic actions and indications, 95
Aminophylline, 864, 867–869
Amiodarone, 470, 472, 696, 703, 706
Amisulpride, 336, 338
Amitriptyline, 317, 319
Amlodipine, 665, 671, 716, 724
Amnesia, 416, 417
Amoebiasis, 163, 170–171
Amoxycillin, 91, 108, 109, 110
clavulanic acid
(Augmentin)
, and, 93
Amphetamines, 67
Amphotericin B, 152, 155
Ampicillin, 108, 109
Amyl nitrate, 67, 720
Anabolic steroids, 67
male reproductive system and, 627,
631–634
adverse effects, 631–632, 633–634
care considerations, 632–633
contraindications and cautions, 631
drug–drug interactions, 632
pharmacokinetics, 631
therapeutic actions and indications,
631
Anaemia, 774, 775–777
adults, 779
aetiology, 775–776
children, 779
drugs used to treat, 774–790
erythropoiesis-stimulating agents.
See
Erythropoiesis-stimulating agents
iron-deficiency.
See
Iron-deficiency
anaemia
megaloblastic.
See
Megaloblastic
anaemias
older adults, 779
sickle cell, 777, 789–790
Anaerobic bacteria, 90, 92
Anaesthetic agents, 416–429
adults, 417
anaesthetic, definition, 416
balanced anaesthesia, 416, 418
children, 417
general anaesthesia, 416, 417–419
administration, 418–419
balanced, 418
risk factors, 417–418
general anaesthetic agents, 419–424
anaesthetic gases, 420, 421–422
barbiturate anaesthetics, 419–420
care considerations, 423–424
non-barbiturate anaesthetics,
420–421
volatile liquids, 420, 422–423
local anaesthesia, 416, 424–428
critical thinking exercise, 428–429
field block, 424
infiltration, 424
intravenous regional local anaesthesia,
425
mechanisms of action, 426
nerve block, 424–425
topical administration, 424
local anaesthetic agents, 425–428
adverse effects, 426–427
care considerations, 427–428
contraindications and cautions, 426
