Index
979
Corpus luteum, 596, 599
Corpus striatum, 372, 373
Corticosteroids, 536, 537
adults, 540
children, 540
duration of effect, 539
glucose regulation, 575
older adults, 540
routes of administration, 544
transplant care, 268–269
Corticotropin-releasing hormone (CRH),
522–524
Cortisone, 539, 542, 543, 547
Cost considerations, 60, 65–66
Cough, 834, 836
Countercurrent mechanism, 794,
797–798
COX-1 (cyclooxygenase-1), 246, 249
COX-2 (cyclooxygenase-2), 246–250
Coxiella burnetii (Q fever) vaccine, 279
Cranial nerves, 298
Creatine, 632, 964
Cretinism, 551, 555
CRH.
See
Corticotrophin-releasing
hormone (CRH)
Crotamiton, 952
Culture, 81, 85
Cumulation
drug effects and, 25, 27
Cyanocobalamin, 787, 788
Cyclooxygenase-2 inhibitors, 240
Cyclopentolate, 501, 503, 957
Cyclophosphamide, 195, 196, 198
Cycloplegia, 501, 502
Cyclosporin, 258, 260, 263–265,
268–269
Cyproheptadine, 852, 854
Cystic fibrosis, 834, 839
Cystitis, 819, 820
interstitial, 819, 827
treatment, education regarding,
822–823
Cytarabine, 200, 201, 203
Cytochrome P450, 23
Cytomegalovirus.
See
Herpes and
cytomegalovirus
Cytotoxic reaction, 33, 34
Cytotoxic T cells, 233
D
Dabigatran, 756, 759–760
Dacarbazine, 195, 196
Dactinomycin, 205
Dalteparin, 195, 757–766
Damiana, 632
Danazol, 629
Dandelion root, 582, 964
Dantrolene, 385, 386, 390–392, 423
Dapagliflozin, 587, 588, 589–590
Dapsone, 118, 119
Daptomycin, 121
Darbepoetin alfa, 777–780
Darifenacin, 824, 825
Darunavir, 136, 139
Daunorubicin, 205, 206
DAW (dispensed as written), 10
Decimals, 53, 54
converting to and from fractions, 54
decimal places, 54
dividing, 55
multiplying, 54–55
rounding, 54
Decongestants, 842, 846–852
oral, 842, 847, 849–851
topical nasal, 842, 846–849
topical nasal steroids, 842, 847,
851–852
Degarelix, 212, 213
Delayed allergic reaction, 33, 34
Dendrites, 292, 293
Denominator, 53, 54
Depolarisation, 292, 294
Depolarising neuromuscular junction
(NMJ), 432, 434
blockers, 437–439
adverse effects, 438
care considerations, 439
contraindications and cautions, 438
drug–drug interactions, 438
pharmacokinetics, 438
therapeutic actions and indications,
437–438
Depression, 316, 317
biogenic amine theory, 316, 317
drug therapy, 317
Dermal patch delivery systems, 504
Dermatological reactions, 31, 33–34
Desflurane, 420, 422
Desloratadine, 853, 854
Desmopressin, 521, 523, 530–533
Desogestrel, 607, 608, 611
Desvenlafaxine, 330–331
Devil’s claw, 613
Dexamethasone, 539, 542, 543, 954, 957
Dexamphetamine, 347
Dexchlorpheniramine, 852, 854
Dexmedetomidine, 313
Dextromethorphan, 842, 844, 845
Dextropropoxyphene, 401, 402
DHEA (dehydroepiandrosterone), 964
Di huang, 471, 964
Diabetes insipidus, 521, 530–532
Diabetes mellitus, 572, 573, 576–578
cultural blood glucose variations, 577
hyperglycaemia, 578
hypoglycaemia, 578
type I, 584–585
Diagnostic and Statistical Manual of
Mental Disorders
, 335
Diarrhoea, 916, 917
Diastole, 642, 643
Diazepam, 303, 305–307, 352, 354, 357,
359–360, 362, 386, 388, 389
Diazoxide, 666, 674
DIC (disseminated intravascular
coagulation), 760
Diclofenac, 247, 957
Dicloxacillin, 108, 109
Didanosine, 136, 137
Diffusion, 72, 76–77
facilitated, 77
Digestion, 891
Digestive enzymes, 896, 912–913
adverse effects, 912
care considerations, 913
contraindications and cautions, 912
dysfunction, 897
pharmacokinetics, 912
therapeutic actions and indications, 912
Digoxin, 681, 685–692, 703, 707–708
antidote, 681, 688
chronic antiarrhythmic therapy,
709–711
inadequate absorption, 690–692
toxicity, 688
Digoxin immune fab, 688
Diltiazem, 657, 665, 671–672, 696, 703,
706–707, 714, 716, 724
Dimenhydrinate, 853, 854
Dinoprostone, 606, 620, 622, 623
Dipeptidyl-peptidase-4, 572, 573, 574,
586, 588–589
Diphenhydramine, 842, 853–855
Diphtheria, 274, 279–280
Diphtheria and tetanus toxoids, 279–280
hepatitis B, pertussis, poliomyelitis and
Haemophilus influenzae
vaccine,
280
hepatitis B, pertussis and poliomyelitis
vaccine, 280
pertussis and poliomyelitis vaccine, 280
pertussis vaccine, 280
Dipyridamole, 755, 758
Disopyramide, 702
Disseminated intravascular coagulation
(DIC), 760
Distribution, 15, 22–23
drug–drug or drug–alternative therapy
interactions, 28
Dithranol, 951
Diuretic agents, 658, 675, 803–816
adults, 806
carbonic anhydrase inhibitors, 805,
809, 811, 813
care considerations, 815–816
children, 806
high-ceiling, 803, 809
loop diuretics, 805, 809–811
older adults, 807
osmotic diuretics, 806, 809, 814–15
potassium-sparing diuretics, 806, 809,
813–814
thiazide and thiazide-like diuretics,
803, 805, 807–809
Diurnal rhythm, 512, 516, 536, 537
Dobutamine, 456, 458, 676
Docetaxel, 209
Docusate, 920
Dolasetron, 931, 934
Dolour, 228, 232
Domperidone, 931, 934
Donepezil, 487, 492–496
Dong quai, 613
Dopamine, 297, 455–456, 458–459, 676
dopamine D2 receptor antagonists, 934
Dopaminergic agents, 372, 374–378
adverse effects, 376
care considerations, 377
