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Sildenafil Restores Erection Hardness (ICP)
Sildenafil
l
80
100
ICP
Reduced
ICP
Restored
Hg
40
60
ICP, mm
0
20
200
Nerve stim
60s
100
ow, ml/min
C ff
C ff
0
Blood Fl
• Penile blood flow restriction reduces cavernous nerve-stimulated increases in ICP
• Sildenafil restores erection hardness to control levels
u
u
Wayman C et al. ESSM. 4-7 December 2005. Poster M-05-141.
Preclinical model