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T

The MSKCC experience ; the 2013 paper

Brachytherapy.

2013 Dec 24. S1538-4721

A Ph II t d f l

hi h d t

ase s u y o sa vage g - ose-ra e

brachytherapy for the treatment of locally

recurrent prostate cancer after definitive

t

l b

di th

ex erna eam ra o erapy.

Yamada Y

1

,

Kollmeier MA

2

,

Pei X

2

,

Kan CC

2

,

Cohen GN

3

,

Donat SM

4

,

Cox BW

2

,

Zelefsky MJ

2

.

1

D t

t f R di ti O l

M i l Sl

K tt i

epar men o a a on nco ogy, emor a oan- e er ng

Cancer Center, New York, NY.

METHODS:

Forty two patients with biopsy proven recurrence were

-

-

enrolled on a Phase II study of salvage HDR monotherapy

using iridium-192. Median pretreatment EBRT dose was 8100 cGy

(6840-8640 cGy) and the median time from completion of EBRT to

l

HDR

h

Th

l

i i d f

sa vage

was 73 mont s

.

e protoco prescr pt on ose o

3200 cGy was delivered in four fractions over 30 hours in a

single insertion.

Median follow up after salvage HDR was 36 months

(6-67 months).