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J Contemp Brachytherapy.

2014 Oct;6(3):304-10..

Salvage low-dose-rate (125)I partial prostate brachytherapy

after dose-escalated external beam radiotherapy.

Chang L

1

,

Buyyounouski MK

2

.

1

Department of Radiation Oncology Fox Chase Cancer Center

,

,

Philadelphia, PA, USA.

2

Department of Radiation Oncology, Stanford University, Stanford, CA,

USA.

PURPOSE:

To report outcomes on 5 patients treated with salvage partial

low dose rate (LDR) 125 iodine ((125)I) permanent prostate

-

-

-

seed brachytherapy (BT) for biopsy-proven locally persistent

prostate cancer, following failure of dose-escalated external

beam radiotherapy (EBRT).

CONCLUSIONS:

In carefully selected patients with local

persistence of disease, partial LDR (125)I

permanent prostate seed implant appears to be a

feasible option for salvage local therapy with an

acceptable toxicity profile.