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J Contemp Brachytherapy.
2014 Oct;6(3):304-10..
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Salvage low-dose-rate (125)I partial prostate brachytherapy
after dose-escalated external beam radiotherapy.
•
Chang L
1
,
Buyyounouski MK
2
.
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1
Department of Radiation Oncology Fox Chase Cancer Center
,
,
Philadelphia, PA, USA.
•
2
Department of Radiation Oncology, Stanford University, Stanford, CA,
USA.
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PURPOSE:
•
To report outcomes on 5 patients treated with salvage partial
low dose rate (LDR) 125 iodine ((125)I) permanent prostate
-
-
-
seed brachytherapy (BT) for biopsy-proven locally persistent
prostate cancer, following failure of dose-escalated external
beam radiotherapy (EBRT).
•
CONCLUSIONS:
•
In carefully selected patients with local
persistence of disease, partial LDR (125)I
permanent prostate seed implant appears to be a
feasible option for salvage local therapy with an
acceptable toxicity profile.