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What is your preferred management for a patient aged 66

years presenting with a PSA of 13.6, Gleason score 4+3

prostate cancer which is stage T2B on MR staging? He has

no significant co-morbidities

a) Radical prostatectomy

b) Active surveillance

c) External beam IMRT to 78Gy

d) LDR seed brachytherapy

e) External beam IMRT + HDR boost