974-975 / 2001
Rationale for study
/f
• High dose raction may be
radiobiologically
advantageous
• Multiple randomised
controlled trials demonstrate
increased prostate cancer
cure rates with higher doses
of radiation
• Studies have shown that
biological behaviour of
prostate cancer may be
driven by dominant lesion
Karavitakis, M.
et al.
(2010) Tumor focality in prostate
cancer: implications for focal therapy
Nat. Rev. Clin. Oncol.
doi:10.1038/nrclinonc.2010.190