103 / 208
Evidence for the use of PN in the PICU
101
5
Supplementary Table 1.
Search strategy
Ovid MEDLINE search strategy
((Critically ill OR critical illnesses OR “Critical Care”[Mesh:NoExp] OR critical care[tiab]
OR “Intensive Care”[Mesh:NoExp] OR intensive care[tiab] OR icu[tiab] OR “Intensive
Care Units”[Mesh:NoExp] OR burn unit OR burn center* OR sepsis) AND (children OR
toddler*[tiab] OR “Infant”[Mesh:NoExp] OR infant[tiab] OR infants[tiab] OR “Infant,
Newborn”[Mesh:NoExp] OR newborn[tiab] OR newborns[tiab] OR neonate[tiab] OR
neonates[tiab] OR newborn[tiab] OR newborns[tiab] OR babies[tiab] OR baby[tiab]
OR adolescents OR teen[tiab] OR teenager[tiab] OR teenagers[tiab] OR youth[tiab] OR
pediatric[tiab] OR paediatric[tiab])) OR “Intensive Care Units, Pediatric”[Mesh:NoExp] OR
PICU[tiab]
86939
AND
(“Parenteral Nutrition”[Mesh:NoExp] OR “Parenteral Nutrition, Total”[Mesh:NoExp]
OR parenteral feeding*[tiab] OR intravenous feeding*[tiab] OR “Parenteral Nutrition
Solutions”[Mesh])
1339
AND
(“randomized controlled trials as topic”[MeSH Terms] OR (“randomized”[All Fields] AND
“controlled”[All Fields] AND “trials”[All Fields] AND “topic”[All Fields]) OR “randomized
controlled trials as topic”[All Fields] OR (“randomized”[All Fields] AND “controlled”[All
Fields] AND “trial”[All Fields]) OR “randomized controlled trial”[All Fields])
131
Alternative:
(Randomized Controlled Trials as Topic OR Random Allocation OR Double Blind Method OR
Single Blind Method OR clinical trial OR clinical trial, phase i[Publication Type] OR clinical
trial, phase ii[Publication Type] OR clinical trial, phase iii[Publication Type] OR clinical trial,
phase iv[Publication Type] OR controlled clinical trial[Publication Type] OR randomized
controlled trial[Publication Type] OR multicenter study[Publication Type] OR clinical trial
[Publication Type] OR Clinical Trials as topic OR (clinical AND trial*) OR ((singl* OR doubl*
OR treb* OR tripl*) AND (blind* OR mask*)) OR placebos OR placebo* OR randomly
allocated OR (allocated AND random*))
213
Ovid EMBASE search strategy
#56
#54 AND #55
468
#55
‘clinical trial’/exp OR ‘clinical trial’ OR ‘randomized controlled trial’/exp OR ‘randomized
controlled trial’ OR ‘randomization’/exp OR’randomization’ OR ‘single blind procedure’/
exp OR ‘single blind procedure’ OR ‘double blind procedure’/exp OR ‘double blind
procedure’ OR ‘crossover procedure’/exp OR ‘crossover procedure’ OR ‘placebo’/exp
OR ‘placebo’ OR (randomi?ed AND controlledAND trial* AND [embase]/lim) OR (rct AND
[embase]/lim) OR (‘random allocation’/exp OR ‘random allocation’ AND [embase]/lim) OR
(‘randomly allocated’ AND [embase]/lim) OR (‘allocated randomly’ AND [medline]/lim) OR
(allocated NEAR/2 random AND [embase]/lim) OR (‘single blind$’ AND [embase]/lim) OR
(‘double blind$’ AND [embase]/lim) OR ((treble OR triple) NEAR/2 blind$ AND [embase]/
lim) OR (placebo$ AND [embase]/lim) OR ‘prospective study’/exp OR ‘prospective
study’ NOT (‘case study’/exp OR ‘case study’ OR (‘case report’/exp OR ‘case report’ AND
[embase]/lim) OR ‘abstract report’/exp OR ‘abstract report’ OR ‘letter’/exp OR ‘letter’)
1,607,926
#54
#52 AND #53
2,848
#53
#40 OR #41 OR #42 OR #43 OR #44 OR #45 OR #46 OR #47 OR #48
42,795
#52
#38 OR #39 OR #51
99,572