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Reward modulation of cognitive function: adult ADHD
processing (i.e. task switching) in the dorsal striatum of adult patients with ADHD, who
carry the 9R ADHD risk allele. This deficit is remediated when patients are tested ON
methylphenidate. These findings demonstrate an important role for both reward motivation
as well as inter-individual trait differences in striatal dopamine transmission in cognitive
processing deficits in adult ADHD.