186 / 1835
311
305
HD7: Long-term Outcome
311
290
15-year estimate [95%-CI]
Arm A:
52.2% [44.9% to 59.5%]
Arm B: 72.8% [65.6% to 80.0%]
diff:
20.6% [10.4% to 30.9%]
HR = 0.45 [0.332 to 0.612]
Median observation time 120 months
15-year estimate [95%-CI]
Arm A:
71.1% [71.2% to 83.0%]
Arm B: 79.7% [73.9% to 85.6%]
diff:
2.7% [-5.7% to 11.0%]
HR = 0.813 [0.560 to 1.179]
Median observation time 136 months
Significantly superior 15-year PFS with CMT compared to EF-RT only
No significant difference in 15-year overall survival (OS) observed
PFS
OS
Bröckelmann et al; EHA 2016